Scutellarin Increases Cisplatin-Induced Apoptosis and Autophagy to Overcome Cisplatin Resistance in Non-small Cell Lung Cancer via ERK/p53 and c-met/AKT Signaling Pathways

Cisplatin, as the first-line anti-tumor agent, is widely used for treatment of ds durga hand soap a variety of malignancies including non-small cell lung cancer (NSCLC).However, the acquired resistance has been a major obstacle for the clinical application.Scutellarin is a active flavone extracted from Erigeron breviscapus Hand-Mazz that has been s

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A single mutation in the 15S rRNA gene confers nonsense suppressor activity and interacts with mRF1 the release factor in yeast mitochondria

We have determined nightstick twm-850xl the nucleotide sequence of the mim3-1 mitochondrial ribosomal suppressor, acting on ochre mitochondrial mutations and one frameshift mutation in Saccharomyces cerevisiae.The 15s rRNA suppressor gene contains a G633 to C transversion.Yeast mitochondrial G633 corresponds to G517 of the E.coli 15S rRNA, which is

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Altered Soil Properties Inhibit Fruit Set but Increase Progeny Performance for a Foundation Tree in a Highly Fragmented Landscape

Failing to test multiple or non-standard variables in studies that investigate the effects of habitat fragmentation on plant populations may limit the detection of unexpected causative relationships.Here, we investigated the impacts of habitat fragmentation on the pollination, reproduction, mating system and progeny performance of Eucalyptus wandoo

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Education against Disinformation

In the contemporary world, disinformation has serious consequences, including undermining democracy, the economy and public health.They influence electoral processes, undermine trust in companies, encourage divisions and divert attention from key issues.Social networks play a key role in spreading disinformation and lack of transparency.Prevention

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